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NICK Nick Schulz is the Editor of Tech Central Station and has worked in media circles and the ideas industry as a writer, editor, television producer and policy analyst. His writings have appeared in The Wall Street Journal, The Los Angeles Times, The Washington Post, Slate, The National Post of Canada, The Baltimore Sun, Investor's Business Daily, The Washington Times, National Review, Reason, Policy Review, and several other publications. He is also, it should be said, a rabid sports fan whose fandom is inversely proportional to his overall athletic ability.
In the Pipeline: Don't miss Derek Lowe's excellent commentary on drug discovery and the pharma industry in general at In the Pipeline

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July 22, 2004

Hercules Was a Big Fat Phony Made of Cheese and Sliced Baloney...

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Posted by Nick

When Alcmene gave birth to the baby... she named him Herakles. (The Romans pronounced the name "Hercules," and so do we today.) ...she tried to kill the baby by sending snakes into his crib. But little Hercules was one strong baby, and he strangled the snakes, one in each hand, before they could bite him.
-- Perseus Digital Library

MEET BABY HERCULES!!

OK, not quite. But it's like some bad sci-fi comic. A German boy was recently found to have a genetic defect that prevents his muscle mass from going and going and going:

Somewhere in Germany is a baby Superman, born in Berlin with bulging arm and leg muscles. Not yet 5, he can hold seven-pound weights with arms extended, something many adults cannot do. He has muscles twice the size of other kids his age and half their body fat.

DNA testing showed why: The boy has a genetic mutation that boosts muscle growth...

The boy's mutant DNA segment was found to block production of a protein called myostatin that limits muscle growth. The news comes seven years after researchers at Johns Hopkins University in Baltimore created buff "mighty mice" by "turning off" the gene that directs cells to produce myostatin.

"Now we can say that myostatin acts the same way in humans as in animals," said the boy's physician, Dr. Markus Schuelke, a professor in the child neurology department at Charite/University Medical Center Berlin. "We can apply that knowledge to humans, including trial therapies for muscular dystrophy."

The AP article reporting the story goes a little over the top when it says:

...athletes would almost surely want to get their hands on such a drug and use it like steroids to bulk up.

We're nowhere near athletes being able to use these sorts of things effectively. But it's certainly the direction we're heading. In the meantime, you'll have to settle for Steak-orade.

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